WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:
Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway       Name:Cell adhesion molecules (CAMs)       ID:04514
C=133; O=6; E=0.21; R=29.04; rawP=6.57e-08; adjP=4.60e-07
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
3  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
4  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
5  ENSG00000154654 NA NCAM2 neural cell adhesion molecule 2 4685 ENSG00000154654
6  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910


Database:KEGG pathway       Name:Glycosphingolipid biosynthesis - ganglio series       ID:00604
C=15; O=2; E=0.02; R=85.82; rawP=0.0002; adjP=0.0007
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111728 NA ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 6489 ENSG00000111728
2  ENSG00000117069 NA ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 81849 ENSG00000117069


Database:KEGG pathway       Name:Protein digestion and absorption       ID:04974
C=81; O=2; E=0.13; R=15.89; rawP=0.0071; adjP=0.0154
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000092758 NA COL9A3 collagen, type IX, alpha 3 1299 ENSG00000092758
2  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626


Database:KEGG pathway       Name:Neuroactive ligand-receptor interaction       ID:04080
C=272; O=3; E=0.42; R=7.10; rawP=0.0088; adjP=0.0154
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000113494 NA PRLR prolactin receptor 5618 ENSG00000113494
3  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873


Database:KEGG pathway       Name:Jak-STAT signaling pathway       ID:04630
C=155; O=2; E=0.24; R=8.31; rawP=0.0244; adjP=0.0342
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137070 NA IL11RA interleukin 11 receptor, alpha 3590 ENSG00000137070
2  ENSG00000113494 NA PRLR prolactin receptor 5618 ENSG00000113494


Database:KEGG pathway       Name:Cytokine-cytokine receptor interaction       ID:04060
C=265; O=2; E=0.41; R=4.86; rawP=0.0641; adjP=0.0748
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137070 NA IL11RA interleukin 11 receptor, alpha 3590 ENSG00000137070
2  ENSG00000113494 NA PRLR prolactin receptor 5618 ENSG00000113494


Database:KEGG pathway       Name:Metabolic pathways       ID:01100
C=1130; O=4; E=1.76; R=2.28; rawP=0.0989; adjP=0.0989
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100577 NA GSTZ1 glutathione S-transferase zeta 1 2954 ENSG00000100577
2  ENSG00000111728 NA ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 6489 ENSG00000111728
3  ENSG00000117069 NA ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 81849 ENSG00000117069
4  ENSG00000158825 NA CDA cytidine deaminase 978 ENSG00000158825




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).